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Product Name
Anti-DOHH Rabbit antibody
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Description
DOHH Rabbit polyclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human
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Alternative names
HLRC1; hDOHH antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human DOHH
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IP: 1/20
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Validations
Western blot detection of DOHH in K562,Hela cell lysates using DOHH Rabbit pAb(1:1000 diluted).Predicted band size:33kDa.Observed band size:33kDa.
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Background
Swiss-Prot Acc.Q9BU89.Catalyzes the hydroxylation of the N6-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine (PubMed:16533814, PubMed:16371467, PubMed:19706422). Hypusination is unique to mature eIF-5A factor and is essential for its function .
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"