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Product Name
Anti-DIS3L2 antibody
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Description
Mouse monoclonal antibody to DIS3L2
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Tested applications
WB, IHC-P, FC
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Species reactivity
Human
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Alternative names
FAM6A antibody; PRLMNS antibody; hDIS3L2 antibody
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Isotype
Mouse IgG1
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Preparation
This antigen of this antibody was recombinant protein
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Clonality
Monoclonal
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Formulation
Liquid, 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
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Storage instructions
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
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Applications
WB: 1:500-1:1,000
IHC-P: 1:50-1:200
FC: 1:100-1:200
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Validations
Fig1: Western blot analysis of DIS3L2 on human DIS3L2 recombinant protein using anti-DIS3L2 antibody at 1/1,000 dilution.
Fig2: Western blot analysis of DIS3L2 on HEK293 (1) and DIS3L2-hIgGFc transfected HEK293 (2) cell lysate using anti-DIS3L2 antibody at 1/1,000 dilution.
Fig3: Western blot analysis of DIS3L2 on Hela (1) and HepG2 (2) cell lysate using anti-DIS3L2 antibody at 1/1,000 dilution.
Fig4: Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissue using anti-DIS3L2 antibody. Counter stained with hematoxylin.
Fig5: Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-DIS3L2 antibody. Counter stained with hematoxylin.
Fig6: Flow cytometric analysis of Jurkat cells with DIS3L2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
- Background
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References
- Du Toit A. Cytoskeleton: Formins induce nuclear actin assembly. Nat Rev Mol Cell Biol 14(6):328 (2013).
- Astuti D et al. Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. Nat Genet 44(3):277-84 (2012).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"