-
Product Name
Anti-Cytochrome P450 17A1/CYP17A1 Rabbit antibody
- Documents
-
Description
Cytochrome P450 17A1/CYP17A1 Rabbit polyclonal antibody
-
Tested applications
WB, IHC-P, ICC/IF, FC, IP
-
Species reactivity
Human, Mouse, Rat
-
Alternative names
CPT7; CYP17; S17AH; P450C17 antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human Cytochrome P450 17A1
-
Clonality
Polyclonal
-
Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
-
Applications
WB: 1/1000-1/5000
IHC: 1/20
ICC/IF: 1/20
FC: 1/20
IP: 1/20
-
Validations
Western blot detection of Cytochrome P450 17A1/CYP17A1 in K562,C6,3T3 cell lysates using Cytochrome P450 17A1/CYP17A1 Rabbit pAb(1:1000 diluted).Predicted band size:57kDa.Observed band size:55kDa.
Immunocytochemistry of Cytochrome P450 17A1(green) in Hela cells using Cytochrome P450 17A1 Rabbit pAb at dilution 1/50, and DAPI(blue)
-
Background
Swiss-Prot Acc.P05093.Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"