Anti-Cytochrome P450 17A1/CYP17A1 Rabbit antibody

Cat.#: 167378

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Product Information

  • Product Name
    Anti-Cytochrome P450 17A1/CYP17A1 Rabbit antibody
  • Documents
  • Description
    Cytochrome P450 17A1/CYP17A1 Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    CPT7; CYP17; S17AH; P450C17 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Cytochrome P450 17A1
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000-1/5000

    IHC: 1/20

    ICC/IF: 1/20

    FC: 1/20

    IP: 1/20

  • Validations

    Western blot detection of Cytochrome P450 17A1/CYP17A1 in K562,C6,3T3 cell lysates using Cytochrome P450 17A1/CYP17A1 Rabbit pAb(1:1000 diluted).Predicted band size:57kDa.Observed band size:55kDa.

    Western blot detection of Cytochrome P450 17A1/CYP17A1 in K562,C6,3T3 cell lysates using Cytochrome P450 17A1/CYP17A1 Rabbit pAb(1:1000 diluted).Predicted band size:57kDa.Observed band size:55kDa.

    Immunocytochemistry of Cytochrome P450 17A1(green) in Hela cells using Cytochrome P450 17A1 Rabbit pAb at dilution 1/50, and DAPI(blue)

    Immunocytochemistry of Cytochrome P450 17A1(green) in Hela cells using Cytochrome P450 17A1 Rabbit pAb at dilution 1/50, and DAPI(blue)

  • Background
    Swiss-Prot Acc.P05093.Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"