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Anti-COX IV (4D11) Mouse antibody

Cat.#: 169079

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Product Information

  • Product Name
    Anti-COX IV (4D11) Mouse antibody
  • Documents
  • Description
    COX IV (4D11) Mouse monoclonal antibody
  • Tested applications
    WB, FC, ICC/IF, IP, IHC-P
  • Species reactivity
    Human, Mouse, Rat, Hamster, Goat, Monkey
  • Alternative names
    AL024441;COX 4;COX IV 1;COX IV;COX IV-1;Cox4;COX41_HUMAN;Cox4a;COX4B;COX4I1;COX4I2; COX4L2;COXIV;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit 4 isoform 1 mitochondrial;Cytochrome c oxidase subunit 4 isoform 1 antibody; mitochondrial;Cytochrome antibody
  • Isotype
    Mouse IgG1
  • Preparation
    Antigen: A synthetic peptide corresponding to carboxyl terminal residues of human COX IV
  • Clonality
    Monoclonal
  • Formulation
    Purified mouse monoclonal antibody in buffer containing 0.1M Tris-Glycine(pH 7.4 150 mM NaCl)with 0.02% sodium azide 0.1mg/mlBSA and 50% glycerol.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000

    ;ICC: 1/150

    ;FC: 1/100

  • Validations

    Western blot detection of COX IV in Mouse skeletal muscel and Jurkat lysates using COX IV mouse mAb (1:1000 diluted). Predicted band size: 17KDa.Observed band size: 17KDa.

    Western blot detection of COX IV in Mouse skeletal muscel and Jurkat lysates using COX IV mouse mAb (1:1000 diluted). Predicted band size: 17KDa.Observed band size: 17KDa.

    Flow Cytometry analysis of K562 cells stained with COX4 (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.

    Flow Cytometry analysis of K562 cells stained with COX4 (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.

    Immunohistochemical analysis of paraffin-embedded human colorectal carcinoma with COX IV Mouse mAb (4D11-B3-E8,1:50 diluted),showing cytoplasm localization.A high pressure mediated antigen retrieval step was performed in citrate buffer(pH6.0).

    Immunohistochemical analysis of paraffin-embedded human colorectal carcinoma with COX IV Mouse mAb (4D11-B3-E8,1:50 diluted),showing cytoplasm localization.A high pressure mediated antigen retrieval step was performed in citrate buffer(pH6.0).

    Immunoprecipitation analysis of Hela cell lysates using COX IV mouse mAb.

    Immunoprecipitation analysis of Hela cell lysates using COX IV mouse mAb.

    Immunocytochemistry of HeLa cells using anti-COX IV mouse mAb diluted 1:150.

    Immunocytochemistry of HeLa cells using anti-COX IV mouse mAb diluted 1:150.

    Western blot detection of COX IV in Goat muscle,CHO-k1,COS7,3T3,Hela,C6 and K562 cell lysates using COX IV mouse mAb (1:5000 diluted).Predicted band size:17KDa.Observed band size:17KDa.

    Western blot detection of COX IV in Goat muscle,CHO-k1,COS7,3T3,Hela,C6 and K562 cell lysates using COX IV mouse mAb (1:5000 diluted).Predicted band size:17KDa.Observed band size:17KDa.

  • Background
    Swiss-Prot Acc.P13073.This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
  • References
    • Inhibiting autophagy increases epirubicin's cytotoxicity in breast cancer cellsAbnormal CYP11A1 gene expression induces excessive autophagy, contributing to the pathogenesis of preeclampsia

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"