Anti-CKMT2 (3F4) Mouse antibody

Anti-CKMT2 (3F4) Mouse antibody

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CKMT2 (3F4) Mouse monoclonal antibody

WB

Rat

CKMT 2;Basic-type mitochondrial creatine kinase;CKMT 2;CKMT2;CPK;Creatine kinase mitochondrial 2;Creatine kinase mitochondrial 2 (sarcomeric);Creatine kinase S-type; creatine kinase S-type antibody; mitochondrial;KCRS_HUMAN;Mib CK;Mib-CK;mitochondrial; OTTHUMP0000 antibody

Mouse IgG2b

Antigen: Purified recombinant human CKMT2 protein fragments expressed in E.coli.

Monoclonal

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol

Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Swiss-Prot Acc.P17540.Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.