Anti-CHI3L1 antibody

Anti-CHI3L1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Mouse CHI3L1

WB

Mouse CHI3L1 / YKL40

HCGP-3P antibody; YKL40 antibody; YYL-40 antibody; gp39 antibody; gp39 antibody; ASRT7 antibody; AW208766 antibody; Brp39 antibody; CHI3L1 antibody; CHI3L1 antibody; DKFZp686N19119 antibody; FLJ38139 antibody; HC-gp39 antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Mouse CHI3L1 / YKL40 . CHI3L1 / YKL40 specific IgG was purified by Mouse CHI3L1 / YKL40 affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.