Anti-CEACAM1 antibody

Anti-CEACAM1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Monoclonal to Rat CEACAM1

FCM

Rat CEACAM‑1/CD66a

bb-1 antibody; Bgp antibody; BGP antibody; BGP1 antibody; Bgp1 antibody; BGPI antibody; Cc1 antibody; C-CAM antibody; CD66a antibody; CD66a antibody; Cea1 antibody; Cea-1 antibody; Cea7 antibody; Cea-7 antibody; Ceacam1 antibody; CEACAM1 antibody; Hv2 antibody; Hv-2 antibody; mCEA1 antibody; Mhv-1 antibody; MHVR antibody; MHVR1 antibody; mmCGM1 antibody; mmCGM1a antibody; mmCGM2 antibody; CEACAM‑1 antibody; CC1 antibody; BGP antibody; BGP1 antibody; BGPI antibody; Bgp antibody; Hv2 antibody; Bgp1 antibody; Cea1 antibody; Cea7 antibody; Hv-2 antibody; MHVR antibody; bb-1 antibody; C-CAM antibody; CD66a antibody; Cea-1 antibody; Cea-7 antibody; MHVR1 antibody; Mhv-1 antibody; mCEA1 antibody; mmCGM1 antibody; mmCGM2 antibody; mmCGM1a antibody

Mouse IgG1

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CEACAM‑1/CD66a . The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Monoclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.

Immune Checkpoint
Immune Checkpoint Detection: ELISA Antibodies   Immune Checkpoint Detection: IHC Antibodies   Immune Checkpoint Detection: ICC Antibodies   Immune Checkpoint Detection: FCM Antibodies   Immune Checkpoint Detection: WB Antibodies
Immune Checkpoint Proteins
Immune Checkpoint Targets   Co-inhibitory Immune Checkpoint Targets

Immunotherapy   Cancer Immunotherapy   Targeted Therapy