Anti-CD8a / Lyt2 antibody

Anti-CD8a / Lyt2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit monoclonal to CD8a / Lyt2

FCM

Ferret CD8a / Lyt2

p32 antibody; CD8a antibody; CD8A antibody; Leu2 antibody; BB154331 antibody; CD8 antibody; Ly-2 antibody; Ly-35 antibody; MAL antibody; Ly-B antibody; Lyt-2 antibody; p32 antibody; Ly-2 antibody; Ly-B antibody; Ly-35 antibody; Lyt-2 antibody; BB154331 antibody; CD8 antibody; MAL antibody; Leu2 antibody

Rabbit IgG

This antibody was obtained from a rabbit immunized with purified, recombinant Ferret CD8a / Lyt2 (rF CD8a / Lyt2; ABS50091.1; Met1-Glu186) and conjugated with APC under optimum conditions, the unreacted APC was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

Human T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I  membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.