Anti-CD79a Rabbit antibody

Cat.#: 168940

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Product Information

  • Product Name
    Anti-CD79a Rabbit antibody
  • Documents
  • Description
    CD79a Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC
  • Species reactivity
    Human
  • Alternative names
    IGA; MB-1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human CD79a
  • Clonality
    Monoclonal
  • Formulation
    50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    WB: 1/1000-1/2000

    IHC: 1/20-1/50

    ICC/IF: 1/100

    FC: 1/20

  • Validations

    Western blot detection of CD79a in Jurkat cell lysates using CD79a Rabbit mAb(1:500 diluted).Predicted band size:25kDa.Observed band size:45-55kDa.

    Western blot detection of CD79a in Jurkat cell lysates using CD79a Rabbit mAb(1:500 diluted).Predicted band size:25kDa.Observed band size:45-55kDa.

  • Background
    Swiss-Prot Acc.P11912.Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"