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Product Name
Anti-CD58 antibody
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Description
Mouse Monoclonal to Human CD58
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Tested applications
FCM
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Species reactivity
Human LFA-3 / CD58
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Alternative names
LFA3 antibody; ag3 antibody; CD58 antibody; CD58 antigen antibody; CD58 molecule antibody; LFA3 antibody; LFA-3 antibody; lymphocyte function-associated antigen 3 antibody; RP5-1086K13.2 antibody; surface glycoprotein LFA-3 antibody
- Immunogen
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Isotype
Mouse IgG1
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Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LFA-3 / CD58 and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed.
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Clonality
Monoclonal
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Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
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Storage instructions
This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. -
Applications
FCM
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Validations
Human LFA-3 / CD58 Flow Cytometry (FC) 15900
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Background
CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"