-
Product Name
Anti-CD53 antibody
- Documents
-
Description
Rabbit Monoclonal to Cynomolgus CD53
-
Tested applications
WB, ELISA, IP
-
Species reactivity
Cynomolgus CD53
-
Alternative names
AI323659 antibody; antigen MOX44 identified by monoclonal antibody MRC-OX44 antibody; Cd53 antibody; CD53 antibody; CD53 antigen antibody; CD53 antigen antibody; CD53 glycoprotein antibody; CD53 molecule antibody; CD53 tetraspan antigen antibody; cell surface antigen antibody; cell surface glycoprotein CD53 antibody; cell surface glycoprotein CD53 antibody; leukocyte surface antigen CD53 antibody; leukocyte surface antigen CD53 antibody; MOX44 antibody; Ox-44 antibody; tetraspanin-25 antibody; transmembrane glycoprotein antibody; TSPAN25 antibody; Tspan25 antibody; tspan-25 antibody; MOX44 antibody; TSPAN25 antibody; Ox-44 antibody; Tspan25 antibody; AI323659 antibody
- Immunogen
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Cynomolgus CD53 .
-
Clonality
Monoclonal
-
Formulation
0.2 μm filtered solution in PBS
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA: 0.1-0.2 μg/ml
This antibody can be used at 0.1-0.2 μg/ml with the appropriate secondary reagents to detect Cynomolgus CD53.
IP: 1-4 μl/mg of lysate
-
Validations
Cynomolgus CD53 Immunoprecipitation(IP) 14821
CD53 Antibody, Rabbit MAb, Western blot
-
Background
CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"