Anti-CD46 antibody

Anti-CD46 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse monoclonal to CD46

FCM

Human CD46

MCP antibody; AHUS2 antibody; CD46 antibody; Cd46 antibody; Mcp antibody; MGC26544 antibody; MIC10 antibody; TLX antibody; TRA2.10 antibody; MCP antibody; TLX antibody; AHUS2 antibody; MIC10 antibody; TRA2.10 antibody; Mcp antibody

Mouse IgG1

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD46 (rh CD46; EAW93471.1; Met 1-Asp 328) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Monoclonal

Aqueous solution containing 0.5% BSA and 0.09% sodium azide

This antibody is stable for 12 months from date of receipt when stored at 2℃-8℃. Protected from prolonged exposure to light. Do not freeze !
Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

FCM

CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.