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Anti-Caspase 10 Rabbit antibody

Cat.#: 167311

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-Caspase 10 Rabbit antibody
  • Documents
  • Description
    Caspase 10 Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, FC, IP
  • Species reactivity
    Human
  • Alternative names
    MCH4; ALPS2; FLICE2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human Caspase-10
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/2000

    IHC: 1/20

    FC: 1/50

    IP: 1/20

  • Validations

    Immunohistochemistry of Caspase-10 in paraffin-embedded Human lung cancer tissue using Caspase-10 Rabbit pAb at dilution 1/20

    Immunohistochemistry of Caspase-10 in paraffin-embedded Human lung cancer tissue using Caspase-10 Rabbit pAb at dilution 1/20

    Western blot detection of Caspase 10 in K562 cell lysates using Caspase 10 Rabbit pAb(1:1000 diluted).Predicted band size:59kDa.Observed band size:59kDa.

    Western blot detection of Caspase 10 in K562 cell lysates using Caspase 10 Rabbit pAb(1:1000 diluted).Predicted band size:59kDa.Observed band size:59kDa.

  • Background
    Swiss-Prot Acc.Q92851.Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"