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Product Name
Anti-Calnexin Rabbit antibody
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Description
Calnexin Rabbit polyclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human, Rat
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Alternative names
CNX; P90; IP90 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Calnexin
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
FC: 1/50
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Validations
Western blot detection of Calnexin in K562 cell lysates using Calnexin Rabbit pAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:90kDa.
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Background
Swiss-Prot Acc.P27824.Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.SitesFeature keyPosition(s)Description
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"