Anti-BRAT1 Rabbit antibody

Cat.#: 166830

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-BRAT1 Rabbit antibody
  • Documents
  • Description
    BRAT1 Rabbit polyclonal antibody
  • Tested applications
    WB, ICC/IF, FC, IP
  • Species reactivity
    Human
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human BRAT1
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/2000-1/10000

    ICC/IF: 1/50

    FC: 1/20

    IP: 1/20

  • Validations

    Immunocytochemistry of BRAT1(green) in Hela cells using BRAT1 Rabbit pAb at dilution 1/50, and DAPI(blue)

    Immunocytochemistry of BRAT1(green) in Hela cells using BRAT1 Rabbit pAb at dilution 1/50, and DAPI(blue)

    Western blot detection of BRAT1 in K562 cell lysates using BRAT1 Rabbit pAb(1:1000 diluted).Predicted band size:88kDa.Observed band size:88kDa.

    Western blot detection of BRAT1 in K562 cell lysates using BRAT1 Rabbit pAb(1:1000 diluted).Predicted band size:88kDa.Observed band size:88kDa.

  • Background
    Swiss-Prot Acc.Q6PJG6.Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"