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Product Name
Anti-BLBP/FABP7 antibody
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Description
Rabbit polyclonal to BLBP/FABP7
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Tested applications
ELISA, WB
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Species reactivity
Human BLBP / FABP7
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Alternative names
MRG antibody; Blbp antibody; BFABP antibody; B-FABP antibody; MRG antibody; BLBP antibody; FABPB antibody; B-FABP antibody; LTR2-FABP7 antibody; BFABP antibody; B-FABP antibody; B-FABP antibody; Blbp antibody; BLBP antibody; brain antibody; brain antibody; brain lipid binding protein antibody; brain lipid binding protein antibody; brain-type fatty acid-binding protein antibody; brain-type fatty acid-binding protein antibody; Fabp7 antibody; FABP7 antibody; FABPB antibody; fatty acid binding protein 7 antibody; fatty acid binding protein 7 antibody; fatty acid-binding protein antibody; fatty acid-binding protein antibody; mammary-derived growth inhibitor related antibody; mammary-derived growth inhibitor-related antibody; MRG antibody; MRG antibody; RP11-548E19.1 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human BLBP / FABP7 (rh BLBP / FABP7; O15540; Met1-Ala132). BLBP / FABP7 specific IgG was purified by Human BLBP / FABP7 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS with 5% trehalose
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 10-20 μg/ml
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human BLBP / FABP7. The detection limit for Human BLBP / FABP7 is < 0.039 ng/well.
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Validations
BLBP / FABP7 Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
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Background
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake, transport, and metabolism. BLBP is expressed, during development, in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.
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References
- Shi YE, et al. (1997) Antitumor activity of the novel human breast cancer growth inhibitor, mammary-derived growth inhibitor-related gene, MRG. Cancer Res. 57(15):3084-91.
- Young JK, et al. (1997) Immunoreactivity for brain-fatty acid binding protein in gomori-positive astrocytes. Glia. 16(3):218-26.
- Xu LZ, et al. (1996) Ligand specificity of brain lipid-binding protein. J Biol Chem. 271(40): 24711-9.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"