Anti-ATP6V1A Rabbit antibody
ATP6V1A Rabbit monoclonal antibody
WB, IHC-P, ICC/IF, FC, IP
Human, Mouse, Rat
HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1 antibody
Antigen: Recombinant protein of human ATP6V1A
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
Western blot detection of ATP6V1A in K562,Rat Brain,3T3 cell lysates using ATP6V1A Rabbit mAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:68kDa.
Swiss-Prot Acc.P38606.Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). May play a role in neurite development and synaptic connectivity (PubMed:29668857).
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