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  • Anti-ATP6V1A Rabbit antibody

Anti-ATP6V1A Rabbit antibody

Cat.#: 168918

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Special Price 441.3 USD

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Product Information

  • Product Name
    Anti-ATP6V1A Rabbit antibody
  • Documents
  • Description
    ATP6V1A Rabbit monoclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF, FC, IP
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    HO68; VA68; VPP2; Vma1; ARCL2D; ATP6A1; IECEE3; ATP6V1A1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human ATP6V1A
  • Clonality
    Monoclonal antibody
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
  • Applications

    1:1000

    1:200

    1:50

    1:20

    1:20

  • Validations

    Western blot detection of ATP6V1A in K562,Rat Brain,3T3 cell lysates using ATP6V1A Rabbit mAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:68kDa.

    Western blot detection of ATP6V1A in K562,Rat Brain,3T3 cell lysates using ATP6V1A Rabbit mAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:68kDa.

  • Background
    Swiss-Prot Acc.P38606.Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633). May play a role in neurite development and synaptic connectivity (PubMed:29668857).
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"