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Product Name
Anti-ASH2L Rabbit antibody
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Description
ASH2L Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
ASH2; Bre2; ASH2L1; ASH2L2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human ASH2L
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/2000-1/10000
IHC: 1/20
ICC/IF: 1/50
FC: 1/200
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Validations
Immunocytochemistry of ASH2L(green) in Hela cells using ASH2L Rabbit pAb at dilution 1/50, and DAPI(blue)
Western blot detection of ASH2L in C6,3T3,Hela cell lysates using ASH2L Rabbit pAb(1:1000 diluted).Predicted band size:69kDa.Observed band size:80kDa.
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Background
Swiss-Prot Acc.Q9UBL3.Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"