Anti-ART4 antibody

Anti-ART4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Mouse Monoclonal to Rat ART4

IHC-P

Rat CD297

DO antibody; DOK1 antibody; ARTC4 antibody; CD297 antibody; DO antibody; DOK1 antibody; ARTC4 antibody; 4432404K01Rik antibody; mono(ADP-ribosyl)transferase antibody; 4432404K01Rik antibody; ADP-ribosyltransferase 4 (DO blood group) antibody; CD297 antibody; DO antibody; DO antibody; DOK1 antibody; DOK1 antibody; Dombrock blood group carrier molecule antibody; ecto-ADP-ribosyltransferase 4 antibody; ecto-ADP-ribosyltransferase 4 antibody; mono(ADP-ribosyl)transferase 4 antibody; mono-ADP-ribosyltransferase 4 antibody; NAD(P)(+)--arginine ADP-ribosyltransferase 4 antibody

Mouse IgG1

This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat CD297 . The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.

Monoclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

ADP-ribosyltransferase 4 (Dombrock blood group), also known as Mono-ADP-ribosyltransferase 4(ART4), Dombrock blood group carrier molecule and CD297, is a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. ART4 could be detected on HEL cells and erythrocytes by FACS analysis while it was absent from activated monocytes, despite the presence of ART4 mRNA in these cells. ART is also known as the carrier of the Dombrock blood group alloantigens (Do) which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane.