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Product Name
Anti-AP3M1 Rabbit antibody
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Description
AP3M1 Rabbit polyclonal antibody
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Tested applications
WB, ICC/IF, FC
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Species reactivity
Human
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human AP3M1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
ICC/IF: 1/50
FC: 1/20
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Validations
Western blot detection of AP3M1 in K562,C6,3T3,Hela cell lysates using AP3M1 Rabbit pAb(1:1000 diluted).Predicted band size:47kDa.Observed band size:47kDa.
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Background
Swiss-Prot Acc.Q9Y2T2.Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"