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Product Name
Anti-ALKBH4 Rabbit antibody
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Description
ALKBH4 Rabbit monoclonal antibody
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Tested applications
WB, IP
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Species reactivity
Human
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Alternative names
ABH4 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human ALKBH4
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000
1:20
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Validations
Western blot detection of ALKBH4 in K562,Hela cell lysates using ALKBH4 Rabbit mAb(1:1000 diluted).Predicted band size:34kDa.Observed band size:34kDa.
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Background
Swiss-Prot Acc.Q9NXW9.Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"