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Product Name
Anti-ALKBH2 Rabbit antibody
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Description
ALKBH2 Rabbit polyclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human, Mouse, Rat
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human ALKBH2
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
FC: 1/20-1/100
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Validations
Western blot detection of ALKBH2 in C6,3T3,Hela cell lysates using ALKBH2 Rabbit pAb(1:1000 diluted).Predicted band size:29kDa.Observed band size:29kDa.
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Background
Swiss-Prot Acc.Q6NS38.Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"