Anti-AGA antibody

Cat.#: 141418

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Product Information

  • Product Name
    Anti-AGA antibody
  • Documents
  • Description
    Rabbit Polyclonal to Human AGA
  • Tested applications
    ELISA, IHC-P
  • Species reactivity
    Human ASRG / Aspartylglucosaminidase
  • Alternative names
    Aspartylglucosaminidase antibody; AGA antibody; AGU antibody; ASRG antibody; GA antibody; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase antibody; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase antibody; aspartylglucosylamine deaspartylase antibody; glycosylasparaginase antibody; GA antibody; AGU antibody; ASRG antibody; AW060726 antibody; Aspartylglucosaminidase antibody; Aga antibody; AW060726 antibody; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase antibody; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase antibody; glycosylasparaginase antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human ASRG / Aspartylglucosaminidase . ASRG / Aspartylglucosaminidase specific IgG was purified by Human ASRG / Aspartylglucosaminidase affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human ASRG / Aspartylglucosaminidase.

    IHC-P: 0.1-2 μg/mL

  • Validations

    Human ASRG / Aspartylglucosaminidase Immunohistochemistry(IHC) 15223

    Human ASRG / Aspartylglucosaminidase Immunohistochemistry(IHC) 15223

    Human ASRG / Aspartylglucosaminidase Immunohistochemistry(IHC) 15224

    Human ASRG / Aspartylglucosaminidase Immunohistochemistry(IHC) 15224

  • Background
    S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response.

    Human Protein S100-A8, also known as S100 calcium-binding protein A8, Cystic fibrosis antigen, Migration inhibitory factor-related protein 8, S100A8, and CAGA, is a member of the S-100 family. S100A8 plays a role in various functions of myeloid cells by forming a heterocomplex with S100A9. S100A8 and S100A9 are known to be overexpressed in certain species of carcinomas. S100A8 plays an important role in dedifferentiation of thyroid carcinoma possibly by forming a complex with S100A9. S100A8 and S100A9 may also play a key role in inflammation-associated cancer.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"