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Product Name
Anti-Adipose Triglyceride Lipase Rabbit antibody
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Description
Adipose Triglyceride Lipase Rabbit polyclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, IP
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Species reactivity
Human, Mouse, Rat
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Alternative names
ATGL; TTS2; PEDF-R; FP17548; TTS-2.2; iPLA2zeta; 1110001C14Rik antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant protein of human Adipose Triglyceride Lipase
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/1000
IHC: 1/500
ICC/IF: 1/100
IP: 1/20
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Validations
Immunohistochemistry of Adipose Triglyceride Lipase in paraffin-embedded Human breast cancer tissue using Adipose Triglyceride Lipase Rabbit pAb at dilution 1/100
Western blot detection of Adipose Triglyceride Lipase in K562,C6,3T3,Hela cell lysates using Adipose Triglyceride Lipase Rabbit pAb(1:1000 diluted).Predicted band size:55kDa.Observed band size:55kDa.
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Background
Swiss-Prot Acc.Q96AD5.Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674). Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"