-
Product Name
Anti-ADAM8(CD156) antibody
- Documents
-
Description
Rabbit polyclonal to ADAM8(CD156)
-
Tested applications
IHC-P
-
Species reactivity
Human CD156a
-
Alternative names
a disintegrin and metallopeptidase domain 8 antibody; Adam8 antibody; CD156 antibody; CD156a antibody; E430039A18Rik antibody; MS2 antibody; ADAM 8 antibody; a disintegrin and metalloprotease domain (ADAM) 8 antibody; a disintegrin and metalloprotease domain 8 antibody; cell surface antigen MS2 antibody; disintegrin and metalloproteinase domain-containing protein 8 antibody; macrophage cysteine-rich glycoprotein antibody; MS2 antibody; CD156 antibody; CD156a antibody; MS2 antibody; CD156 antibody; ADAM8 antibody; CD156a antibody; E430039A18Rik antibody
-
Isotype
Rabbit IgG
-
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the human CD156a, and purified by antigen affinity chromatography.
-
Clonality
Polyclonal
-
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
-
Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
IHC-P: 0.1-2 μg/ml
-
Validations
CD156a Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Immunochemical staining of human ADAM8 in human placenta with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
CD156a Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
Immunochemical staining of human ADAM8 in human kidney with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).
-
Background
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"