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Product Name
Anti-ADAM8 antibody
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Description
Rabbit Polyclonal to Human ADAM8
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Tested applications
IHC-P, ICC/IF, IF
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Species reactivity
Human ADAM8 / CD156
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Alternative names
a disintegrin and metallopeptidase domain 8 antibody; Adam8 antibody; CD156 antibody; CD156a antibody; E430039A18Rik antibody; MS2 antibody; ADAM 8 antibody; a disintegrin and metalloprotease domain (ADAM) 8 antibody; a disintegrin and metalloprotease domain 8 antibody; cell surface antigen MS2 antibody; disintegrin and metalloproteinase domain-containing protein 8 antibody; macrophage cysteine-rich glycoprotein antibody; MS2 antibody; CD156 antibody; CD156a antibody; MS2 antibody; CD156 antibody; ADAM8 antibody; CD156a antibody; E430039A18Rik antibody
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human ADAM8 / CD156, and purified by antigen affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
IHC-P: 1-5μg/mL
ICC/IF: 0.5-3μg/mL
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Validations
Human ADAM8 / CD156 Immunohistochemistry(IHC) 15601
Human ADAM8 / CD156 Immunofluorescence(IF) 15602
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Background
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"