Anti-ACTA2 antibody

Anti-ACTA2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to ACTA2

WB, IHC-P

human ACTA2

Actvs antibody; a-SMA antibody; SMalphaA antibody; alphaSMA antibody; 0610041G09Rik antibody; AAT6 antibody; ACTSA antibody; MYMY5 antibody

Rabbit IgG

Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human Alpha-Smooth Muscle Actin (ACTA2), and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Actins are globular multi-functional proteins which can be detected in all eukaryotic cells. In vertebrates, there are three main groups of actins that possess slightly different functions: alpha, beta, and gamma. The alpha actins, found in muscle tissues, are a major constituent of the contractile apparatus. Beta-actin, found at the expanding edge of cells, uses the projection of its cellular structure as its mean of mobility. Gamma-actin is found in the filaments of stress fibres. ACTA2 is an alpha actin that is found in skeletal muscle. Expression of alpha skeletal, alpha cardiac, alpha vascular, and gamma enteric actins are restricted to specialized muscle cell type. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Further more, expression of smooth muscle alpha actin is regulated by hormones, cell proliferation, and altered by pathological conditions including oncogenic transformation and atherosclerosis.

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