Angiotensinogen antibody

Angiotensinogen antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Angiotensinogen Mouse Monoclonal antibody. Positive IHC detected in human liver cancer tissue, human kidney tissue, human liver tissue. Positive WB detected in Hepg2 cell. Observed molecular weight by Western-blot: 52 kDa

ELISA, WB, IHC

Human; other species not tested.

AGT antibody; Ang I Angiotensin 2 antibody; Ang II Angiotensin 3 antibody; Ang III antibody; Angiotensin I antibody; Angiotensin II antibody; Angiotensin III antibody; Angiotensinogen antibody; ANHU antibody; Des Asp[1] angiotensin II antibody; FLJ92595 antibody; FLJ97926 antibody; Serpin A8 antibody; SERPINA8 antibody

Mouse IgG2b

This antibody was obtained by immunization of Angiotensinogen recombinant protein (Accession Number: NM_000029). Purification method: Protein A purified.

Monoclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.