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Product Name
Angiopoietin 2 antibody
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Description
Angiopoietin 2 Rabbit Polyclonal antibody. Positive WB detected in HUVEC cells, K-562 cells, mouse brain tissue. Positive IHC detected in human liver cancer tissue, human breast cancer tissue. Positive IF detected in A549 cells, PC-12 cells. Observed molecular weight by Western-blot: 68 kDa
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Tested applications
ELISA, WB, IHC, IF
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
AGPT2 antibody; ANG 2 antibody; ANG2 antibody; angiopoietin 2 antibody; ANGPT2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Angiopoietin 2 recombinant protein (Accession Number: NM_001147). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
IF: 1:10-1:100
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Validations
HUVEC cells were subjected to SDS PAGE followed by western blot with Catalog No:108052(ANGPT2 Antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using Catalog No:108052(ANGPT2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using Catalog No:108052(ANGPT2 Antibody) at dilution of 1:50 (under 40x lens)
Immunofluorescent analysis of A549 cells using Catalog No:108052(ANGPT2 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Angiopoietin 2 is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). It disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis.
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