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Angiogenin antibody

Cat.#: 108050

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Product Information

  • Product Name
    Angiogenin antibody
  • Documents
  • Description
    Angiogenin Rabbit Polyclonal antibody. Positive WB detected in human vein tissue, human heart tissue, mouse liver tissue. Positive IHC detected in human liver tissue, mouse testis tissue. Observed molecular weight by Western-blot: 17-20 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    ALS9 antibody; ANG antibody; Angiogenin antibody; HEL168 antibody; Ribonuclease 5 antibody; RNase 5 antibody; RNASE4 antibody; RNASE5 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_001385272). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:50-1:500

  • Validations

    human vein tissue were subjected to SDS PAGE followed by western blot with Catalog No:108050(ANG antibody) at dilution of 1:300

    human vein tissue were subjected to SDS PAGE followed by western blot with Catalog No:108050(ANG antibody) at dilution of 1:300

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:108050(ANG Antibody) at dilution of 1:100 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:108050(ANG Antibody) at dilution of 1:100 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:108050(ANG Antibody) at dilution of 1:100 (under 40x lens).

    Immunohistochemistry of paraffin-embedded human liver tissue slide using Catalog No:108050(ANG Antibody) at dilution of 1:100 (under 40x lens).

  • Background
    Angiogenin (ANG), a angiogenic ribonuclease, is a member of the vertebrate-specific, secreted RNASE superfamily. Angiogenin, originally identified as a tumor angiogenic factor, was related with the growth and metastasis of numerous tumors. Angiogenin is also a component of normal human plasma and follicular Xuid. Its widespread expression in human tissues suggests angiogenin may have biological functions in addition to the promotion of angiogenesis. Recently, its biological activity has been extended to stimulating cell proliferation and promoting cell survival. It is a 17 kDa precursor which is cleaved to generate the 14 kDa mature protein.
  • References
    • Qian D, Gong J, He Z. Bone Marrow-Derived Mesenchymal Stem Cells Repair Necrotic Pancreatic Tissue and Promote Angiogenesis by Secreting Cellular Growth Factors Involved in the SDF-1 α /CXCR4 Axis in Rats. Stem cells international. 2015:306836. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"