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Product Name
Alpha galactosidase A antibody
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Description
Alpha galactosidase A Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells. Positive IF detected in HepG2. Observed molecular weight by Western-blot: 49kd
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Tested applications
ELISA, WB, IF
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Alpha galactosidase A antibody; galactosidase antibody; alpha antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Alpha galactosidase A recombinant protein (Accession Number: NM_000169). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:10-1:100
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107871(GLA antibody) at dilution of 1:1500
Immunofluorescent analysis of HepG2 cells, using GLA antibody Catalog No:107871 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
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Background
GLA, also named as Melibiase, Agalsidas and Alpha-galactosidase A, Belongs to the glycosyl hydrolase 27 family. It hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids. Fabry disease is an X-linked lysosomal storage disorder resulting from the deficient activity of GLA. Enzyme replacement therapy (ERT) with GLA is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease.
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