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Product Name
Human SerpinF2 (His Tag) recombinant protein
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Description
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
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Protein name
Alpha-2-antiplasmin
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Protein short names
ALPHA-2-PI; AAP; API; PLI; SERPINF2; SERPIMF2; AI747498; A2AP; RP23-384C18.2
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Uniprot ID
P08697
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Gene Name
SERPINF2; AAP; PLI
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SerpinF2 (NP_000925.2) (Met 1-Lys 491) was expressed, with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The recombinant human SerpinF2 consists of 475 amino acids after removal of the signal peptide and predicts a molecular mass of 53.2 kDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rhSerpinF2 is approximately 70 kDa due to glycosylation.
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Purity
> 97 % as determined by SDS-PAGE
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Activity
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate,Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Anaspec, Catalog#27114). The IC50 value is < 0.5 nM.
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Validations
Human SerpinF2 / SERPINF2 Protein (His Tag) SDS-PAGE
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