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Product Name
ALOX5 antibody
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Description
ALOX5 Mouse Monoclonal antibody. Positive WB detected in pig spleen tissue. Observed molecular weight by Western-blot: 78 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Pig; other species not tested.
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Alternative names
5 lipoxygenase antibody; 5 LO antibody; 5 LOX antibody; 5LPG antibody; ALOX5 antibody; arachidonate 5 lipoxygenase antibody; LOG5 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of ALOX5 recombinant protein (Accession Number: NM_000698). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
pig spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:107573(ALOX5 Antibody) at dilution of 1:2000
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Background
ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"