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Human AKR1A1 (His Tag) recombinant protein

Cat.#: 502799

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Product Information

  • Product Name
    Human AKR1A1 (His Tag) recombinant protein
  • Documents
  • Description
    Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
  • Protein name
    Alcohol dehydrogenase [NADP(+)]
  • Protein short names
    RP4-697E16.2; MGC12529; DD3; ALR; MGC1380; ARM; HEL-S-6; 2610201A18RIK; AKR1A4; ALDR1
  • Uniprot ID
    P14550
  • Gene Name
    AKR1A1; ALDR1; ALR
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human AKR1A1 (P14550) (Met 1-Tyr 325) was expressed, with a polyhistidine tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human AKR1A1 consisting of 341 amino acids and migrates as an approximately 39 kDa band in SDS-PAGE under reducing conditions as predicted.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Validations

    Human AKR1A1 Protein (His Tag) SDS-PAGE

    Human AKR1A1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"