Cart 2

AKR7A2 Polyclonal Antibody

Cat.#: 161020

Size:

Special Price 174.2 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    AKR7A2 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to AKR7A2
  • Tested applications
    WB, IHC, IF
  • Species reactivity
    Human, Mouse
  • Alternative names
    AKR7A2 antibody; AFAR antibody; AFAR1 antibody; AFB1-AR1 antibody; AKR7 antibody; aldo-keto reductase family 7 member A2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-359 of human AKR7A2 (NP_003680.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:10 - 1:100
  • Validations

    Western blot - AKR7A2 Polyclonal Antibody

    Western blot - AKR7A2 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using AKR7A2 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .

    Immunohistochemistry - AKR7A2 Polyclonal Antibody

    Immunohistochemistry - AKR7A2 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse heart using AKR7A2 antibody at dilution of 1:100 (40x lens).

    Immunofluorescence - AKR7A2 Polyclonal Antibody

    Immunofluorescence - AKR7A2 Polyclonal Antibody

    Immunofluorescence analysis of HeLa cells using AKR7A2 antibody . Blue: DAPI for nuclear staining.

  • Background
    Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"