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Product Name
AKR1C1 Polyclonal Antibody
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Description
Polyclonal antibody to AKR1C1
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Tested applications
WB
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Species reactivity
Human, Mouse
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Alternative names
AKR1C1 antibody; 2-ALPHA-HSD antibody; 20-ALPHA-HSD antibody; C9 antibody; DD1 antibody; DD1/DD2 antibody; DDH antibody; DDH1 antibody; H-37 antibody; HAKRC antibody; HBAB antibody; MBAB antibody; aldo-keto reductase family 1 member C1 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C1 (NP_001344.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:1000 - 1:3000
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Validations
Western blot - AKR1C1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using AKR1C1 antibody at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
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Background
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"