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AKAP8L antibody

Cat.#: 107935

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Product Information

  • Product Name
    AKAP8L antibody
  • Documents
  • Description
    AKAP8L Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells. Positive IF detected in HEK-293 cells. Observed molecular weight by Western-blot: 72 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    A kinase anchor protein 8 like antibody; AKAP8 like protein antibody; AKAP8L antibody; DKFZp434L0650 antibody; HA95 antibody; HAP95 antibody; Helicase A binding protein 95 antibody; Homologous to AKAP95 protein antibody; NAKAP antibody; NAKAP95 antibody; Neighbor of AKAP95 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of AKAP8L recombinant protein (Accession Number: NM_014371). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:1000

    IF: 1:20-1:200

  • Validations

    PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107935(AKAP8L Antibody) at dilution of 1:300

    PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107935(AKAP8L Antibody) at dilution of 1:300

    Immunofluorescent analysis of HEK-293 cells using Catalog No:107935(AKAP8L Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

    Immunofluorescent analysis of HEK-293 cells using Catalog No:107935(AKAP8L Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Background
    AKAP8L, also named as NAKAP, or NAKAP95, is a 646 amino acid protein, which contains two C2H2 AKAP95-type zinc fingers and belongs to the AKAP95 family. AKAP8L localizes in the nucleus matrix and is expressed in the brain cortex. AKAP8L could play a role in constitutive transport element (CTE)-mediated gene expression. AKAP8L may be involved in nuclear envelope breakdown and chromatin condensation. It also may regulate the initiation phase of DNA replication when associated with TMPO-beta.
  • References
    • Xing L, Zhao X, Guo F, Kleiman L. The role of A-kinase anchoring protein 95-like protein in annealing of tRNALys3 to HIV-1 RNA. Retrovirology. 11:58. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"