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ADRA1A-Specific antibody

Cat.#: 107888

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Product Information

  • Product Name
    ADRA1A-Specific antibody
  • Documents
  • Description
    ADRA1A-Specific Rabbit Polyclonal antibody. Positive FC detected in HepG2 cells. Positive WB detected in mouse brain tissue, mouse heart tissue. Observed molecular weight by Western-blot: 52 kDa
  • Tested applications
    ELISA, WB, FC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ADRA1A antibody; ADRA1C antibody; ADRA1L1 antibody; Alpha 1A adrenergic receptor antibody; Alpha 1A adrenOCeptor antibody; Alpha 1A adrenoreceptor antibody; Alpha 1C adrenergic receptor antibody; Alpha adrenergic receptor 1c antibody; ALPHA1AAR antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Peptide (Accession Number: NM_000680). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107888(ADRA1A-Specific antibody) at dilution of 1:300

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107888(ADRA1A-Specific antibody) at dilution of 1:300

    1X10^6 HepG2 cells were stained with 0.2ug ADRA1A-Specific antibody (Catalog No:107888, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

    1X10^6 HepG2 cells were stained with 0.2ug ADRA1A-Specific antibody (Catalog No:107888, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.

  • Background
    ADRA1A, also named as ADRA1C, belongs to the G-protein coupled receptor 1 family. ADRA1A mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. The antibody is specific to ADRA1A.
  • References
    • Wang JJ, Chen XL, Xu CB. The ERK1/2 pathway participates in the upregulation of the expression of mesenteric artery α1 receptors by intravenous tail injections of mmLDL in mice. Vascular pharmacology. 77:80-8. 2016.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"