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Product Name
Human ADA / Adenosine deaminase (His Tag) recombinant protein
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Description
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
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Protein name
Adenosine deaminase
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Protein short names
RP23-144O20.2; ADENOSINE AMINOHYDROLASE; ADENOSINE DEAMINASE; ADA
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Uniprot ID
P00813
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Gene Name
ADA; ADA1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ADA (P00813) (Met1-Leu363) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Human
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Molecular weight
The secreted recombinant human ADA consists of 373 amino acids and predicts a molecular mass of 42.1 KDa. The apparent molecular mass of the protein is approximately 44 KDa in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human ADA / Adenosine deaminase Protein (His Tag) SDS-PAGE
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