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Product Name
Adenosine A1 Receptor antibody
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Description
Adenosine A1 Receptor Rabbit Polyclonal antibody. Positive IHC detected in mouse brain tissue, mouse cerebellum tissue, mouse testis tissue. Positive WB detected in SH-SY5Y cells. Observed molecular weight by Western-blot: 37 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Adenosine A1 Receptor antibody; Adenosine receptor A1 antibody; ADORA1 antibody; RDC7 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_000674). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:50-1:500
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Validations
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:107784(ADORA1 antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:107784(ADORA1 Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:107784(ADORA1 Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Background
ADORA1, also named as RDC7, is a receptor for adenosine. It is mediated by G proteins which inhibit adenylyl cyclase. Adenosine is an important mediator of ethanol intoxication and exerts some of its effects via ADORA1 in the central nervous system. The antibody is specific to ADORA1.
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References
- Burke TM, Markwald RR, McHill AW. Effects of caffeine on the human circadian clock in vivo and in vitro. Science translational medicine. 7(305):305ra146. 2015.
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