ADAMTS1 Polyclonal Antibody
Polyclonal antibody to ADAMTS1
ADAMTS1 antibody; C3-C5 antibody; METH1 antibody; ADAM metallopeptidase with thrombospondin type 1 motif 1 antibody
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 718-967 of human ADAMTS1 (NP_008919.3).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:200 - 1:2000
Western blot - ADAMTS1 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using ADAMTS1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 1s.
Cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
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