Human DBI / ACBD1 (His Tag) recombinant protein

Human DBI / ACBD1 (His Tag) recombinant protein

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Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.

Acyl-CoA-binding protein

ACYL-COENZYME A BINDING PROTEIN); ACYL-COA-BINDING PROTEIN; DIAZEPAM BINDING INHIBITOR (GABA RECEPTOR MODULATOR; ACBD1; ACYL-COENZYME A BINDING DOMAIN CONTAINING 1; ACYL-COA BINDING PROTEIN); DIAZEPAM BINDING INHIBITOR; TRYPSIN-SENSITIVE; EP; ACYL COENZYME A BINDING PROTEIN; ACBP; ACYL-COA BINDING PROTEIN; CHOLECYSTOKININ-RELEASING PEPTIDE; CCK-RP; ENDOZEPINE; SPLICE FORM 1B; DIAZEPAM-BINDING INHIBITOR; DBI; GABA RECEPTOR MODULATOR

P07108

DBI

E. coli

A DNA sequence encoding the human DBI (P07108-2) (Met1-Ala87) was expressed with a polyhistidine tag at the N-terminus.

Human

The recombinant human DBI consists of 122 amino acids and predicts a molecular mass of 14 KDa. It migrates as an approximately 18 KDa band in SDS-PAGE under reducing conditions.

> 95 % as determined by SDS-PAGE