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Product Name
Human SUB1 / PC4 (His Tag) recombinant protein
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Description
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
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Protein name
Activated RNA polymerase II transcriptional coactivator p15
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Protein short names
RPO2TC1; RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR; ACTIVATED RNA POLYMERASE II TRANSCRIPTION COFACTOR 4; P9; SUB1 HOMOLOG (S. CEREVISIAE); P15; P14; AI842364; SINGLE-STRANDED DNA-BINDING PROTEIN P9; PC4; POSITIVE COFACTOR 4; ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15; SUB1
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Uniprot ID
P53999
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Gene Name
SUB1; PC4; RPO2TC1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human SUB1 (P53999) (Met1-Leu127) was expressed with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SUB1 consists of 142 amino acids and predicts a molecular mass of 16.2 KDa. It migrates as an approximately 19 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human SUB1 Protein (His Tag) SDS-PAGE
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