ACOT11 antibody

Cat.#: 107743

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Product Information

  • Product Name
    ACOT11 antibody
  • Documents
  • Description
    ACOT11 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IHC detected in human prostate cancer tissue.
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    ACOT11 antibody; acyl CoA thioesterase 11 antibody; BFIT antibody; BFIT1 antibody; BFIT2 antibody; KIAA0707 antibody; STARD14 antibody; THEA antibody; THEM1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of ACOT11 recombinant protein (Accession Number: BC001517). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:107743(ACOT11 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:107743(ACOT11 antibody) at dilution of 1:100 (under 10x lens)

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107743(ACOT11 Antibody) at dilution of 1:1000

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:107743(ACOT11 Antibody) at dilution of 1:1000

  • Background
    ACOT11(Acyl-coenzyme A thioesterase 11) is also named as BFIT, KIAA0707, THEA.BFIT is mapped to syntenic regions of chromosomes 1 (human) and 4 (mouse) associated with body fatness and diet-induced obesity, potentially linking a deficit of BFIT activity with exacerbation of these traits and supports the transition of this tissue towards increased metabolic activity, probably through alteration of intracellular fatty acyl-CoA concentration(PMID:11696000).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"