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Product Name
ACE antibody
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Description
ACE Rabbit Polyclonal antibody. Positive IP detected in mouse heart tissue. Positive WB detected in mouse heart tissue. Observed molecular weight by Western-blot: 170 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
ACE antibody; ACE1 antibody; Angiotensin converting enzyme antibody; CD143 antibody; DCP antibody; DCP1 antibody; Dipeptidyl carboxypeptidase I antibody; Kininase II antibody; MVCD3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ACE recombinant protein (Accession Number: NM_152831). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IP: 1:500-1:5000
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:107735(ACE Antibody) at dilution of 1:1000
IP Result of anti-ACE (IP:Catalog No:107735, 4ug; Detection:Catalog No:107735 1:1000) with mouse heart tissue lysate 4000ug.
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Background
ACE(Angiotensin-converting enzyme) is also named as DCP, DCP1 and belongs to the peptidase M2 family. It is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. ACE also has a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. It has 4 isoforms produced by alternative splicing. The full length protein has 15 glycosylation sites and it can show a molecular weight of 170 kDa(PMID:16804085).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"