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Product Name
ACADSB Polyclonal Antibody
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Description
Polyclonal antibody to ACADSB
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Tested applications
IF
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Species reactivity
Human
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Alternative names
ACADSB antibody; 2-MEBCAD antibody; ACAD7 antibody; SBCAD antibody; acyl-CoA dehydrogenase, short/branched chain antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 133-432 of human ACADSB (NP_001600.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
IF 1:50 - 1:200
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Validations
Immunofluorescence - ACADSB Polyclonal Antibody
Immunofluorescence analysis of HeLa cells using ACADSB antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Background
Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"