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Product Name
ABCD1 antibody
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Description
ABCD1 Mouse Monoclonal antibody. Positive WB detected in Hela cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 75 kDa
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Tested applications
ELISA, WB, IF
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Species reactivity
Human; other species not tested.
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Alternative names
ABC42 antibody; ABCD1 antibody; Adrenoleukodystrophy protein antibody; ALD antibody; ALDP antibody; AMN antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of ABCD1 recombinant protein (Accession Number: NM_000033). Purification method: Caprylic acid/ammonium sulfate precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IF: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107556(ABCD1 antibody) at dilution of 1:400
Immunofluorescent analysis of (-20oc Ethanol) fixed HeLa cells using Catalog No:107556(ABCD1 Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"