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  • Abaecin peptide

Abaecin peptide

For research use only. We do not sell to patients.

Cat.#: 303368

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Optional Service: TFA RemovalWhat's this?

Special Price 430.1 USD

Availability: 4 weeks
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Product Information

  • Product Name
    Abaecin peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    YVPLPNVPQPGRRPFPTFPGQGPFNPKIKWPQGY
  • Three letter code
    H-Tyr-Val-Pro-Leu-Pro-Asn-Val-Pro-Gln-Pro-Gly-Arg-Arg-Pro-Phe-Pro-Thr-Phe-Pro-Gly-Gln-Gly-Pro-Phe-Asn-Pro-Lys-Ile-Lys-Trp-Pro-Gln-Gly-Tyr-OH
  • Length (aa)
    34
  • Peptide Purity (HPLC)
    97.6
  • Molecular Formula
    C187H270N48O43
  • Molecular Weight
    3878.4
  • Source
    Synthetic
  • Additional Information
    Rich in P. Active against A. tumefaciens Gembloux A, E. salicis NCPPB 2530, E. coli NCTC 9001 (MIC 25-50 ug/ml), E. coli NCTC 9001*, E. coli K514 (MIC 10-25 ug/ml), P. syringae pv. tomamta NCPPB 1105 (MIC 25-50 ug.ml), X. campestris pv. vesicatoria LMG 905 (MIC 5-10 ug/ml), and Gram-positive bacteria B. megaterium OMB 1551 (MIC 10-25 ug/ml) and M. luteus (M. lysodeikticus) LMG 4050 (MIC 10-25 ug/ml). Thus, the highest observed specific activity of the peptide was against an apidaecin-resistant Xanthomonas strain. Relish regulates expression of antimicrobial peptide genes in the honeybee, Apis mellifera, shown by RNA interference (Insect Mol Biol. 2007 Dec;16(6):753-9). APD Updated 10/2008. name corrected 5/2014 GW. Abaecin has Antibacterial activity. Abaecin was found in honeybee, Apis mellifera L..
  • Storage Guidelines
    Ideally Abaecin peptide should be stored in a freezer at or below -9C. Abaecin peptide should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Casteels P, Ampe C, Riviere L, et al. Isolation and characterization of abaecin, a major antibacterial response peptide in the honeybee (Apis mellifera). Eur J Biochem. 1990;187(2):381-6.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

Peptide Property

  • Analysed Sequence:H-YVPLPNVPQPGRRPFPTFPGQGPFNPKIKWPQGY-OH
  • Chemical Formula:C187H270N48O43
  • Sequence length:34
  • Extinction coefficient:8250 M-1cm-1
  • GRAVY:-0.91
  • Mw average:3878.42
  • Theoretical pI:10.78
  • Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

Red: Hydrophobic uncharged residues, like F I L M V W A and P

Blue: Basic residues, like R K H and N-terminal -NH2

Green: Acidic residues, like D E and C-terminal -COOH

Black: Polar uncharged residues, like G S T C N Q and Y

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"