-
Product Name
A2BP1 antibody
- Documents
-
Description
A2BP1 Rabbit Polyclonal antibody. Positive IP detected in mouse brain tissue. Positive IHC detected in mouse brain tissue, human brain tissue. Observed molecular weight by Western-blot: 45-50 kDa
-
Tested applications
ELISA, IHC, IP
-
Species reactivity
Human, Mouse; other species not tested.
-
Alternative names
A2BP antibody; A2BP1 antibody; ataxin 2 binding protein 1 antibody; Fox 1 homolog A antibody; FOX1 antibody; HRNBP1 antibody; RBFOX1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of A2BP1 recombinant protein (Accession Number: NM_145893). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
IP: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
IP Result of anti-A2BP1 (IP:Catalog No:107665, 4ug; Detection:Catalog No:107665 1:500) with mouse brain tissue lysate 4000ug.
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using Catalog No:107665(A2BP1 Antibody) at dilution of 1:200 (under 10x lens).
-
Background
A2BP1, also named as FOX1 and HRNBP1, contains one RRM (RNA recognition motif) domain. A2BP1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. A2BP1 and ataxin-2 are both localized in the trans-Golgi network. This is a rabbit polyclonal antibody raised against the N terminus of human A2BP1.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"