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Product Name
ZMAT3 antibody
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Description
ZMAT3 Rabbit Polyclonal antibody. Positive IP detected in mouse testis tissue. Positive WB detected in mouse testis tissue, HEK-293 cells. Observed molecular weight by Western-blot: 32kd
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ12296 antibody; p53 activated gene 608 protein antibody; PAG608 antibody; WIG 1 antibody; WIG1 antibody; Zinc finger protein WIG 1 antibody; zinc finger antibody; matrin type 3 antibody; ZMAT3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ZMAT3 recombinant protein (Accession Number: NM_022470). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:117067(ZMAT3 antibody) at dilution of 1:800
IP Result of anti-ZMAT3 (IP:Catalog No:117067, 3ug; Detection:Catalog No:117067 1:700) with mouse testis tissue lysate 4000ug.
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Background
ZMAT3 is a p53-induced zinc finger protein, and a role in the TP53-dependent growth regulatory pathway, contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. Acts as a bona fide target gene of p53/TP53.
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References
- Prahl M, Vilborg A, Palmberg C, Jörnvall H, Asker C, Wiman KG. The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA. FEBS letters. 582(15):2173-7. 2008.
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